Lattice Boltzmann method (LBM) has been used successfully in the field of urban flow simulation such as pollutant dispersion in recent years [1] thanks to its interesting numerical properties. However it has mainly been used in case of pollutant dispersion in urban areas (outside flow) rather than for simulation of air quality and natural ventilation inside buildings. This study present the extension of previous work [1] based on the hybrid recursive regularized lattice Boltzmann model (HRR LBM [2]) to the simulation of natural ventilation inside buildings. An aerosol model in Eulerian framework is also implemented in the lattice Boltzmann solver and compared with standard gaseous transport equation previously used. The different LB simulations are validated with experimental [3] and numerical [4] data on a configuration of pollutant release inside a building with open windows immersed in an atmospheric boundary layer. The criteria introduced in Chang and Hanna [5] are used in order to evaluate the performance of the proposed LB model for air quality studies. The obtained results highlights the ability of LBM to be used in natural ventilation applications. [1] J. Jacob, L. Merlier, F. Marlow and P. Sagaut. Lattice Boltzmann Method-Based Simulations of Pollutant Dispersion and Urban Physics, Atmosphere, 2021. [2] J. Jacob, O. Malaspinas and P. Sagaut. A new hybrid recursive regularised Bhatnagar–Gross–Krook collision model for Lattice Boltzmann method-based large eddy simulation. Journal of Turbulence, 2018. [3] Y. Tominaga and B. Blocken. Wind tunnel analysis of flow and dispersion in cross- ventilated isolated buildings: Impact of opening positions. Journal of Wind Engineering and Industrial Applications, 2016. [4] F. Bazdidi-Tehrani, S. Masoumi-Verki and P. Gholomalipour. Impact of opening shape on airflow and pollutant dispersion in a wind-driven cross-ventilated model building: Large eddy simulation. Sustainable Cities and Society, 2020. [5] J. C. Chang and S. R. Hanna. Air quality model performance evaluation. Meteorolgy and Atmospheric Physics, 2004.