Masonry arch bridges represent a large stock of Europe’s in-service infrastructure network for both roadway and railway traffic. Owing to the old age of these bridges, they have experienced severe deterioration over their service life under extreme environmental conditions, as well as the continuously increasing traffic demands. Realistic assessment of masonry arch bridges is a challenging task due to the complex nonlinear response of masonry material and the interaction between the different bridge components, requiring detailed 3D models to achieve accurate results. Detailed 3D mesoscale models [1], which allow for the actual masonry bond, have proved their ability to provide accurate response predictions but at a high computational cost [1]. This renders the use of 3D mesoscale models not suitable for practical assessment. In this paper, 3D mesoscale models are adopted as a baseline for testing the accuracy of simplified lower-level masonry macroscale modelling strategies under various loading scenarios. This study aims to contribute to the development of a multi-level assessment framework for masonry arch bridges, in which multi-scale modelling strategies ranging from detailed mesoscale to fast-running continuum macroscale models are linked. REFERENCES [1] S. Grosman, A. B. Bilbao, L. Macorini, and B. A. Izzuddin, "Numerical modelling of three-dimensional masonry arch bridge structures," Proceedings of the Institution of Civil Engineers. Engineering and computational mechanics, pp. 1-42, 2021.