Fluid-Structure Interaction Simulation of Transcatheter Aortic Valve Implantation Using Smoothed Particle Hydrodynamics
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This study explores the structural and hemodynamic response in patients undergoing transcatheter aortic valve implantation (TAVI) using a fluid-structure interaction (FSI) approach based on smoothed particle hydrodynamics (SPH). Unlike prior studies that assumed rigid components, our SPH model integrates complete fluid-solid interaction between patient-specific anatomy and the TAVI device. Employing the Abaqus\Explicit solver and the Sapien 3 (S3) TAVI device, the study focuses on key parameters such as effective orifice area (EOA), pressure gradient (PG), and geometric orifice area (GOA). The SPH simulations demonstrate the model's capability to realistically simulate the dynamic response of the TAVI device during the cardiac cycle, offering valuable insights into sealing, device dynamics, and aortic root deformation. Overall, the study presents a comprehensive computational framework for TAVI, utilizing SPH for accurate fluid-solid interaction analysis, with potential applications in in-silico testing of biomedical devices.
