Large-Scale Material Extrusion Processes (LS-MEX) are gaining prominence in small-scale production and prototyping, owing to their capability to fabricate component shapes in novel temporal and spatial dimensions through the application of individual tracks on a scale of several millimeters. Unlike established small-scale printing systems featuring individual tracks on the order of 2 mm or less, the thermal energy introduced into the components in LS-MEX persists for a more extended duration. This sustained thermal energy significantly influences microstructural processes, such as the crystallization of semi-crystalline thermoplastics. In this study, we present an analytical model that captures the crystallization kinetics during the ongoing manufacturing process, encompassing both heating and cooling rates. Leveraging this model enables predictions regarding the structural properties of the final product. Our investigation focuses on elucidating the intricate interplay between LS-MEX parameters and microstructural evolution, particularly in terms of the crystallization dynamics of semi-crystalline thermoplastics. The developed analytical model facilitates a nuanced understanding of the temporal aspects of thermal influence, allowing for precise predictions of microstructural changes and, consequently, informed assessments of the final component's material properties. This research contributes valuable insights into optimizing LS-MEX for enhanced control over the fabrication of components with tailored microstructures, opening avenues for advancements in small-scale manufacturing and prototyping.