Since the presentation of Isogeometric Analysis (IGA) by T. Hughes et. al [1], the interest in academia has grown exponentially to explore its use and applications. However, in the industry, and specifically the automotive industry, the level of integration is still low. Industrial CAD components use the Boundary Representation (B-Rep) technique which represent volumes by their boundary surfaces that are constructed defining a visible part of their whole by means of a Boolean operation known as trimming. This has given rise to two main IGA approaches to deal with this type of models: global approaches and local approaches [2]. Global approaches are based on the enhancement of the geometry definition using untrimmed splines technologies. On the other hand, local approaches are based on the enhancement of the analysis capabilities to use the B-Rep discretization as background parametrization while the trimming curves determine the domain of interest. Commercial software widely used in the automotive industry are increasing their IGA capabilities, such as ANSA pre-processor and LS-DYNA numerical solver. This opens the possibility to integrate IGA in the current automotive workflows with either pure-IGA or hybrid FEA-IGA models. However, the industry is still not fully embracing the technology. This work presents some of the findings done in an Industrial PhD between IDIADA and UPC that aims to focus on the key points that remain to be addressed for a wide adoption of IGA in the automotive industry. Such as, modelling guidelines, modelling of component features, cross-talk effect due to trimming technique and crack modelling with IGA. The final objective is to establish an industrial validation for crashworthiness CAE analysis for full vehicle.